منابع مشابه
Compatible solutes and fungal development.
Compatible solutes are components that can be quickly accumulated and degraded inside fungal cells. They do not disturb the functioning of proteins and protect the cell under adverse conditions. In this issue of the Biochemical Journal, Solomon and co-workers evaluate the role of mannitol, one of these components, in Stagonospora nodorum, a plant-pathogenic fungus, and find surprising effects o...
متن کاملProtein stabilization by compatible solutes
Heteronuclear NMR relaxation measurements and hydrogen exchange data have been used to characterize protein dynamics in the presence or absence of stabilizing solutes from hyperthermophiles. Rubredoxin from Desulfovibrio gigas was selected as a model protein and the effect of diglycerol phosphate on its dynamic behaviour was studied. The presence of 100 mM diglycerol phosphate induces a fourfol...
متن کاملProperties of compatible solutes in aqueous solution.
We have performed Molecular Dynamics simulations of ectoine, hydroxyectoine and urea in explicit solvent. Special attention has been spent on the local surrounding structure of water molecules. Our results indicate that ectoine and hydroxyectoine are able to accumulate more water molecules than urea by a pronounced ordering due to hydrogen bonds. We have validated that the charging of the molec...
متن کاملHalophilic bacteria and their compatible solutes – osmoregulation and potential applications
Halophilic bacteria grow over an extended range of salt concentrations. Their metabolic patterns are distinct compared to their terrestrial counterparts and obligate halophiles. The possibility of rapid adjustment to changes in the external salt concentration makes them potential candidates for bioprocessing. Halophilic bacteria produce enzymes, metabolites, solutes, exopolysaccharides and pigm...
متن کاملDiversity and biosynthesis of compatible solutes in hyper/thermophiles.
The accumulation of compatible solutes, either by uptake from the medium or by de novo synthesis, is a general response of microorganisms to osmotic stress. The diversity of compatible solutes is large but falls into a few major chemical categories, such as carbohydrates or their derivatives and amino acids or their derivatives. This review deals with compatible solutes found in thermophilic or...
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ژورنال
عنوان ژورنال: Biochemical Journal
سال: 2006
ISSN: 0264-6021,1470-8728
DOI: 10.1042/bj20061229